Abstract
BackgroundThe influence of fine needle aspiration (FNA) on peritoneal lavage cytology (CY) in pancreatic ductal adenocarcinoma (PDAC) is unknown. MethodsWe retrospectively analyzed 29 patients with resectable left-sided PDAC undergoing FNA prior to CY examination. We assessed clinical factors related to CY+, scored the tumor diameter (<20 mm = 0, ≥20 mm = 1) and examination interval between FNA and CY (>18 days = 0, ≤18 days = 1), and investigated the probability of CY + by the sum of each score (0–2). ResultsThe probability of CY+ was 31%. The CY + group had larger tumors and shorter examination intervals than the CY− group. The CY + probability was 75%, 15%, and 13% for a score of 2, 1, and 0, respectively (P = 0.011). ConclusionA short interval between FNA and CY examination for a large tumor may be a risk factor for CY+ in patients with left-sided PDAC.
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