Abstract

Although exhaled carbon monoxide (CO) is studied from decades, a few studies are about its levels in smokers with obstructive sleep apnea (OSA). The average level of exhaled CO (eCO) was determined in OSA smokers and found increased significantly higher than in patients with other breathing related sleep disorders. A gender significant difference in average eCO was also noticed, with higher numbers in men, in OSA patients. A threshold of the eCO � 6 ppm has 100% specificity and 96.3% sensitivity in detection of the active smoking habit in patients with OSA. Among OSA comorbidities, only chronic obstructive pulmonary disease (COPD) seams to influence the increased eCO levels in OSA active smokers.

Highlights

  • Exhaled carbon monoxide (CO) is studied from decades, a few studies are about its levels in smokers with obstructive sleep apnea (OSA)

  • As there are a few studies concerning the level of CO in smokers with breathing related sleep disorders, the aim of the study was to focuse on the evaluation of the relationship between OSA and exhaled CO in active smokers

  • 53.15+11.47 years, referred to a sleep medicine outpatient center placed in Constanta, Romania, and diagnosed with Breathing related sleep disorders (BRSD), more than a half were identified with obstructive sleep apnea (n=204; 66.66%)

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Summary

Experimental part

The study included adults diagnosed with breathing related sleep disorders (BRSD) in a sleep laboratory who informed consented to be investigated. Cases were considered patients diagnosed with obstructive sleep apneea (OSA), having an apneea - hypopnea index (AHI). The data base contained informations about smoking status, medical history, symptoms, clinical and paraclinical examination, including anthropometric indexes as body mass index (BMI), neck circumference (NC), waist circumference (WC) and eCO measurement. Other BRSD (nonOSA) consisted in upper airways resistance syndrome (UARR), considered if AHI

Results and discussions
OF STUDY GROUP
Conclusions
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