Abstract

Background: Kits (combinations of immune-modulatory compounds: GM-CSF+Picibanil (Kit-I), Prostaglandine (PG-E2,Kit-K) or +PGE1 (Kit-M), patent 102014014993) convert myeloid blasts into dendritic cells of leukemic origin (DCleu). After stimulation with DCleu, antileukemic T-cells can be generated ex vivo. Compounds are approved for clinical use and are attractive tools for immunotherapy in myeloid leukemia.

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