Abstract

Increased carotid intima-media thickness as a predictor for abnormal myocardial perfusion by dobutamine stress echocardiography in patients with diabetes mellitus type 2

Highlights

  • Diabetes is a fast-growing health problem in Egypt with a significant impact on morbidity and mortality

  • Screening tests for early diagnosis of Coronary artery disease (CAD) may lead to early treatment and improved outcomes

  • The findings of this study show that increased carotid intima-media thickness (CIMT) and carotid plaque were significantly related to the presence and extent of abnormal myocardial perfusion, it is reasonable to recommend using CIMT to identify asymptomatic patients with type 2 diabetes mellitus at higher risk for CAD and indirect predictor for cardiovascular events

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Summary

Introduction

Diabetes is a fast-growing health problem in Egypt with a significant impact on morbidity and mortality. The prevalence of type 2 diabetes (T2DM) in Egypt is around 15.6% of all adults aged 20 to 79 [1]. Diabetes mellitus is a powerful risk factor for coronary artery disease and carotid atherosclerosis [2]. Silent myocardial ischemia (SMI) is more common in diabetic patients with a prevalence about 15 % to 22 % [3]. Coronary artery disease (CAD) is usually a late diagnosis in diabetic patients and the disease is usually more advanced at that time [4]. Coronary artery disease (CAD) remains a leading cause of death among patients with diabetes mellitus (DM). Screening tests for early diagnosis of CAD may lead to early treatment and improved outcomes

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