Increased cardiovascular risk factors in breast cancer survivors identified by routine measurements of body composition, resting heart rate and arterial blood pressure.

David H Jones,Sara Henophy,Alain Steve Comtois,Melisa Nestore,Julia Cousin

doi:10.1186/2193-1801-3-150

David H Jones, Sara Henophy + Show 3 more

Open Access

https://doi.org/10.1186/2193-1801-3-150

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Abstract

PurposeThe main objective of this prospective study was to obtain a better understanding of the body composition and vital sign measures of cancers survivors (CS) when compared to regular (R) patients.MethodsA total of 9,315 female patients were evaluated: 476 CS and 8,839 R patients. Kinesiologists worked side by side with the medical/oncology team to collect a number of base-line measurements on body composition, resting heart rate, and blood pressure as part of the standard intake evaluation during the female patients’ annual checkup.ResultsCS were more likely to have a higher BMI (P = 0.001) and a larger waist circumference (P = 0.001) than R patients. CS were also shown to have higher blood pressure values: diastolic pressure of 76.9 mmHg ± 10.5 VS 75.5 mmHg ± 9.9, (P = 0.01) and systolic pressure of 129.8 mmHg ± 17.2 VS 126.7 mmHg ±17.4 (P = 0.001) compared to R patients, respectively. Regression analysis looking at the relationship between mean arterial pressure and waist circumference did not show any difference between the two groups (CS vs R).ConclusionCS who had a higher BMI, a larger waist circumference and higher blood pressure levels, are probably at greater risk for developing cardiovascular disease, diabetes, various musculoskeletal problems as well as an increased risk for various forms of cancers including reoccurrence of previously treated cancer when compared to R patients. Changes in body composition should be considered by the medical team when looking at preventative healthcare strategies for their CS patients.

Highlights

It has been well established that as body composition changes with an increase in waist circumference and an overall increase in body mass index (BMI), there is a greater risk for individuals to develop various metabolic diseases such as diabetes, heart disease, as well as an increased risk of developing cancer or having a reoccurrence of a previously treated cancer (Han et al 2006)
We hypothesized that by measuring body composition and vital signs in women as part of their regular follow-up care and comparing the Cancer Survivors (CS) to the Regular Patients (R) that we would be able to obtain a better understanding of the potential increase of ill health risk that cancer patients face after completing therapy
The BMI values obtained on the patients in this study showed that many of the women were not falling into the recommended guidelines put forward by the ACSM (American College of Sports Medicine 2009)

Summary

Introduction

It has been well established that as body composition changes with an increase in waist circumference and an overall increase in body mass index (BMI), there is a greater risk for individuals to develop various metabolic diseases such as diabetes, heart disease, as well as an increased risk of developing cancer or having a reoccurrence of a previously treated cancer (Han et al 2006). Major health organizations, such as the World Health. The main objective of this prospective study was to obtain a better understanding of the body composition and vital sign measures of CS when compared to R

Results

Discussion

Conclusion