Abstract
Background: A cardiothoracic ratio (CTR) > 0.5 is considered abnormal, and has been associated with poor outcomes in heart failure (HF). An increased CTR may be a marker of other measures of ventricular remodeling and thus confound studies of association of CTR and HF outcomes. The objective of this study was to examine the association of CTR with outcomes in a propensity-matched cohort of HF patients. Methods: In the Digitalis Investigation Group (DIG) trial, 4690 of the 7788 patients with HF had a CTR > 0.5 at baseline.
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