Abstract
In order to investigate the possibility of neurological involvement in the development of ischemic myopathy, the lumbar spinal cord of rats with experimental ischemia of the hind limbs was labeled with [ 3H]leucine and the transport of label down the sciatic nerve monitored. Rapid axoplasmic flow in these rats was increased 2.04-fold while the slow transport component remained unaltered. Administration of 5-hydroxytryptamine to the ischemic rats resulted in a further 15% increase in the rapid transport rate. In both cases, the increased transport rates were associated with elevated serum creatine phosphokinase levels and alterations in protein and lipid turnover of the spinal cord.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
