Abstract

Summary In 8 of 24 patients with cirrhosis of the liver an abnormal pressure gradient between the inferior vena cava and the right atrium, due to elevated pressure in the great veins below the diaphragm, was found. This gradient is thought to be caused partly by constriction of the inferior vena cava by the liver and partly by increased intraabdominal pressure. The significance of the increased pressure in the inferior vena cava in relation to esophageal varices and the formation of ascites and edema is discussed.

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