Abstract

Introduction: Elevated cardiac troponin (cTn) levels are associated with adverse events in patients with chronic and acute decompensated heart failure. Neopterin,a moderator of cellular immune response, predicts future cardiac and vascular adverse events in patients with chronic coronary artery disease. Hypothesis: The aim of this study was to evaluate the prognostic value of neopterin in the setting of acute heart failure by itself and in relation to troponin. Methods: The biomarkers in AHF (BACH trial) was a prospective,15 center, international study of 1641 patients presenting to the ED with dyspnea.

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