Increase in systolic blood pressure and improvement in laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock

Y Sakamoto,K Mashiko,Y Hara,H Yokota,T Obata,H Matsumoto,N Kutsukata

doi:10.1186/cc8305

Abstract

Direct hemoperfusion using a polymyxin B-immobilized fiber column (DHP-PMX; Toray Industries Inc., Tokyo, Japan) was first developed in 1994 and has since been used for the treatment of septic shock.

Highlights

We previously showed that erythropoietin (EPO) attenuates the morphological signs of spinal cord ischemia/reperfusion (I/R) injury in swine [1] without, improving neurological function
We investigated the correlation between various factors and simulation performance using senior medical students
We studied their willingness in four hypothetical scenarios related to the initial three links: early emergency call, cardiopulmonary resuscitation (CPR) under one’s own initiative, telephone-assisted chest compression and use of automated external defibrillator (AED)

Summary

Introduction

We previously showed that erythropoietin (EPO) attenuates the morphological signs of spinal cord ischemia/reperfusion (I/R) injury in swine [1] without, improving neurological function. The aim of this study was to determine the impact of viral respiratory infections in an intensive care setting and the role of systematic viral testing in patients admitted to an ICU. The evidence base for the outcome of critically ill patients with cirrhosis admitted to intensive care (ICU) is currently limited to data from tertiary transplant centres, which report mortality rates of between 45 and 74%. This study aimed to determine the value of early enteral nutrition up to goal on the prognosis of the patients with different severity of illness in the ICU. Since hyperglycemia is known to be associated with immunosuppression and increased risk of life-threatening infections, we aimed to assess the impact of glycemic control (normoglycemia) in ICU patients with sepsis. The first step for the required social dialogue is to search for local customs for harmonisation with ethical and legal regulations, as well as the interests of physicians and patients

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Conclusion