Abstract
The oculomotor nerve was stimulated intracranially with a stereotactic technique in rabbits. Paracentesis was performed after 15 or 30 min of stimulation and the protein concentration of the aqueous humour was measured. The protein content of the aqueous humour increased about twofold in the stimulated eye as compared with the control eye. This increase was not due to the increased tension of the extraocular muscles during stimulation. Neither was the change dependent on the stimulation intensity above the threshold for intense miosis. Pretreatment with indomethacin was always ineffective in preventing the increase in protein concentration. Blockade of the muscarinic receptors with biperiden abolished most of this increase during stimulation. Thus, the increase in protein concentration of the aqueous humour during oculomotor nerve stimulation seems to be due to a cholinergic mechanism.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
