Abstract

Front Cover: In article 1900668 by Dagmar Fischer, Kalina Peneva, and co-workers, the incorporation of indole-based monomers in guanidinium-containing poly(methacrylamide)s leads to highly efficient transfection agents that can condense plasmid DNA even at a nitrogen-to-phosphate (N/P) ratio of 1 and show a 200-fold increase in transfection compared to their guanidinium counterparts. The strong potential of the indole group as a side-chain functionality to increase cellular uptake of polymers is also demonstrated. Graphical representation of the pDNA-polyplex was created by Szymon Wiktorowicz, Labartory.

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