Abstract

To develop a new compressed sensing parallel imaging technique called READ-PICS that can effectively incorporate prior information from a reference scan for MR image reconstruction from highly undersampled multichannel measurements. READ-PICS incorporates information from a high-spatial-resolution reference prior using the generalized series model, to achieve increased image sparsity and mitigated noise amplification simultaneously. To further improve the ill-conditioning of the parallel imaging system, an annular area in the central residual k-space is used for calibration. Additionally, the mixed L1-L2 norm of the coefficients from the prior component and residual component is used to enforce joint sparsity. The evaluations on parametric imaging and multiscan experiment demonstrate superior performance of READ-PICS in terms of detail preservation and noise suppression compared to state-of-the-art technique, L1-Iterative self-consistent parallel imaging reconstruction, and prescan required method, correlation imaging. The proposed method can significantly increase signal sparsity and improve the ill-conditioning of the parallel imaging system using reference adaptive regularization. This technique can be easily adapted to other imaging applications where multiple images need to be acquired sequentially and a reference prior is also available.

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