Inclusion Compounds of Binaphthol with Lutidines − Structures, Selectivity and Kinetics of Desolvation

Abstract

The crystal structures of the inclusion compounds formed between the host 2,2′-dihydroxy-1,1′-binaphthyl (BNP) and three isomers of lutidine − 2,6-, 2,4-, and 3,5-lutidine − have been elucidated and their potential lattice energies calculated. The selectivities of enclathration by the host have been measured by competition experiments. The kinetics of desolvation of the inclusion compounds were studied and activation energies were determined. The results were reconciled in terms of the mode of inclusion and the lattice energies of the host−guest assemblies.