Abstract
Formation of inclusion complexes between several cyclodextrin derivatives and TEMPO and DOXYL-based spin probes was studied by EPR spectroscopy. Competition between alkyl chains and nitroxide functionalities for cyclodextrin cavities leads to different types of complexation. Long alkyl chains in amphiphilic spin probes interact preferentially with cyclodextrins, and TEMPO units in such molecules are unaffected by complexation. DOXYL-type spin probes however form stronger complexes with cyclodextrins; this complexation changes hyperfine splitting and tumbling rate of the nitroxide group. Comparison of EPR spectra of free cyclodextrin and cyclodextrin-based polymeric nanocapsules made it possible to assess the tumbling of the spin probe inside the cyclodextrin units without the contribution of the tumbling of the whole complex.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.