Abstract
A consequence of the late awareness of Chagas disease in North America is that many early studies were never published in peer-reviewed journals and are not easily accessible for inclusion in systematic reviews. We reviewed data from the state of Guanajuato, Mexico, as an illustration. Three population-based surveys have been performed between 1991 and 2002 and were never fully published. Systematic reviews should recognize this publication bias.
Highlights
Chagas disease or American trypanosomiasis is a major cause of cardiac disease in the Americas [1]
Most of the efforts to control Chagas disease have been focused on South and Central America, while the awareness of Chagas disease is more recent in North America, including Mexico [2]
A consequence of the late awareness of Chagas disease in North America is that many early studies were never published in peer-reviewed journals and are not accessible for inclusion in systematic reviews
Summary
Chagas disease or American trypanosomiasis is a major cause of cardiac disease in the Americas [1]. Most of the efforts to control Chagas disease have been focused on South and Central America, while the awareness of Chagas disease is more recent in North America, including Mexico [2]. A recent systematic review of Mexican population-based data from 2006 to 2017 estimated the Trypanosoma cruzi national seroprevalence at 3.4% [1]. Mexico has been divided into “endemic” and “non-endemic” areas for Chagas disease [3].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
