Incipient Enamel Lesions Remineralization using Casein Phosphopeptide Amorphous Calcium Phosphate Cream with and without Fluoride: A Laser Fluorescence Study

Abstract

The aim of this in vitro investigation was to evaluate and compare the incipient enamel lesions remineralized by topical application of casein phospho peptide amorphous calcium phosphate (CPP-ACP) cream with and without fluoride. Sixty caries free teeth were used in the study. They were divided into four groups as positive control negative control and two experimental groups. The samples were demineralized and then remineralized using a CPP-ACP Cream with and without fluoride. The remineralization was evaluated at 7, 14 and 21 days using laser fluorescence. Results of this study showed that the laser fluorescence readings of test samples for remineralization were very highly significant at 14 and 21 days (p < 0.001). The degree of remineralization achieved between CPP-ACP and CPP-ACP with fluoride was statistically significant (p = 0.040) at 21 days.