INCIDENTALLY DIAGNOSED ADENOCARCINOMA PROSTATE AFTER SURGERY FOR CLINICALLY BENIGN PROSTATOMEGALY A 2 YEARS RETROSPECTIVE STUDY

Abstract

Introduction:Prostate cancer (PCa) is the second most common cause of cancer and the sixth leading cause of cancer death among men worldwide. The worldwide PCa burden is expected to grow to 1.7 million new cases and 499 000 new deaths by 2030 simply due to the growth and aging of the global population. Aims: To incidentally diagnose prostate cancer during TURP or open prostatectomy in patients clinically diagnosed with prostatomegaly with severe Lower urinary tract symptoms (LUTS). Methods:This study “Incidental Prostate Cancer” was conducted on 100 patients selectedin Surgery Department at M.L.B. Medical College, Jhansi between January 2020 to June 2021according to the inclusion criteria; patients were first examined clinically followed specific investigation like PSA, Prostate volume measurement before undertaking surgery for Benign prostatic hyperplasia and the resected specimen/chips of prostate were sent for histopathological examination for confirmation of malignancy. Result: The result of this study demonstrated 1 12% incidence of IPC on clinically diagnosed BPH patients. Patient’s age and PSA level were determined to be factors affecting IPC incidence. Compared to other age groups and PSA level groups, IPC incidence was higher in patients aged >60 years and/or with PSA level >4m=ng/mL. A relation between IPC and Gleason GG2 of 50% was determined statistically on histopathological examination. Conclusion: Incidental prostate cancer diagnosis among patients operated for BPH accounts for a significant proportion. PSA levels and patient’s age are valid diagnostic indicators of IPC. Higher Gleason score ………… significantly correlated with IPC.