Abstract

Serous tubal intraepithelial carcinoma is a putative precursor of high-grade serous carcinoma, which is the most common histological type of ovarian or pelvic peritoneal cancer. Serous tubal intraepithelial carcinoma is commonly found in patients with breast cancer susceptibility gene mutations who undergo risk-reducing salpingo-oophorectomy. Incidental serous tubal intraepithelial carcinoma found by a non-prophylactic surgery is rare. A 33-year-old woman referred to our hospital for a diagnosis of ectopic pregnancy. She underwent a laparoscopic right salpingectomy. Pathologically, ectopic pregnancy in the ampulla of the right fallopian tube was confirmed and serous tubal intraepithelial carcinoma was observed in the fallopian tube. Subsequently, she underwent a laparoscopic hysterectomy, bilateral oophorectomy, and left salpingectomy as additional treatment. She has experienced no recurrence thus far for 37 months since the surgery.

Highlights

  • Serous tubal intraepithelial carcinoma is a putative precursor of high-grade serous carcinoma, which is the most common histological type of ovarian or pelvic peritoneal cancer

  • Serous tubal intraepithelial carcinoma is commonly found in patients with breast cancer susceptibility gene mutations who undergo risk-reducing salpingo-oophorectomy

  • Serous tubal intraepithelial carcinoma (STIC) is commonly found in patients with breast cancer susceptibility gene (BRCA) mutations who undergo risk-reducing salpingo-oophorectomy (RRSO)

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Summary

Introduction

Serous tubal intraepithelial carcinoma (STIC) is a putative precursor of high-grade serous carcinoma (HGSC), which is the most common histological type of ovarian or pelvic peritoneal cancer. STIC is commonly found in patients with breast cancer susceptibility gene (BRCA) mutations who undergo risk-reducing salpingo-oophorectomy (RRSO). Incidental STIC found by a non-prophylactic surgery is rare. We present a case of STIC incidentally found by a surgery.

Case Presentation
Pathological Findings
Discussion
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