Abstract
BackgroundCystic fibrosis is an autosomal recessive disorder characterized by chronic progressive multisystem involvement. AH1N1 virus infections caused classic influenza symptoms in the majority of cystic fibrosis patients while others experienced severe outcomes.Case presentationWe report a case of late incidental cystic fibrosis diagnosis in a young Caucasian man suffering from respiratory failure following infection due to AH1N1 influenza virus. The patient was admitted to our department with fever, cough, and dyspnea at rest unresponsive to antibioticsConclusionsLate diagnosis of cystic fibrosis in uncommon. This report highlights the importance of early cystic fibrosis diagnosis to minimize risk of occurrence of potential life-threatening complications.
Highlights
Cystic fibrosis is an autosomal recessive disorder characterized by chronic progressive multisystem involvement
Cystic fibrosis (CF) is a common autosomal recessive disorder caused by mutations of the cystic fibrosis transmembrane regulator gene (CFTR), classified in six subgroups on the basis of biomolecular mechanisms [1]
CF is usually diagnosed at newborn screening (NBS) [2]
Summary
Cystic fibrosis is an autosomal recessive disorder characterized by chronic progressive multisystem involvement. Prognosis and life expectancy seems to be better when the disease is diagnosed in adulthood the disease course is seriously affected by frequent respiratory infections and early bacterial colonization [2, 3]. * Correspondence: dott.carlo.iadevaia@gmail.com 1Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples - Monaldi Hospital, Via L Bianchi, 80131 Naples, Italy Full list of author information is available at the end of the article
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