Abstract
A 52-year-old woman diagnosed with papillary thyroid carcinoma was referred for 131I therapy following total thyroidectomy. She was given 4,810MBq (130mCi) of 131I following 4weeks of thyroid hormone withdrawal. A posttherapy scan showed intense, focal activity in the pelvis and intense, diffuse activity on both sides of the chest, which was localized to the right ovary and both breasts on SPECT/CT examination. She had bilateral nipple pain and a history of antidopaminergic drugs as combination medication for her rheumatoid arthritis and prokinetics during radioiodine therapy. On a 123I whole-body scan 9months later after stopping the drugs, bilateral breast uptake was not visible; however, right ovarian focal uptake was still visualized. Bilateral salpingo-oophorectomy was performed, and revealed struma ovarii with substantial internal necrosis due to radioiodine therapy. This case is interesting as two rare entities, 131I therapy-related struma ovarii and drug-related breast uptake, were simultaneously visualized.
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