Incidental Detection of Temporary Focal FDG Retention in the Spleen.

Abstract

F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is a valuable tool in discriminating malignancy from benign lesion. But because various false-positive results reduce the diagnostic specificity, nuclear medicine physicians should be familiar with possible false-positive cases. Although many cases of high FDG uptake mimicking malignancy have been reported, temporary FDG uptake of normal spleen has not been reported previously. We report herein a phenomenon of temporary intense focal FDG uptake of normal spleen without evidence of metastasis in a 46-year-old woman with a history of anal cancer. (Figs. 1 and ​and22) Fig. 1 a–f A 66-year-old woman underwent a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) study for restaging. She had undergone concurrent chemoradiation therapy for anal cancer 2 months previously. ... Fig. 2 a A whole-body maximum intensity projection (MIP) volume rendering image of the FDG-PET scan shows an intense FDG focus in the splenic hilum. There is no abnormal FDG focus in the other PET field. The high FDG uptake contour along the upper pole of the ...