Abstract
Introduction : Ovarian cancer is the eighth most common malignant disease in women in the world, accounting for 3.4% of all malignant tumors in women. It has the highest lethality among gynecological malignancies. The aim of this paper was to analyze the incidence of this malignancy in the Nisava district in the period 1999-2018. years. Material and method: Descriptive method applied. The population registry for cancer of the Institute of Public Health in Nis was the source of the data. Raw and standardized incidence rates per 100,000 women were calculated. Standardization was performed by the direct method. The linear trend of the incidence rate was calculated. Results: In the structure of malignant diseases in women, ovarian cancer accounts for 5%. The average annual standardized incidence rate is 13.5. In the observed twenty-year period, an increase in the linear trend of incidence rates is registered. The highest standardized rate was recorded in 2016 (20.4), and the lowest in 2002 (10.1). The disease is not registered under the age of fifteen, and is most common in the age group of 70-74. There is a statistically significant increase in the trend of standardized incidence rates with age. The highest standardized incidence rate is recorded in the municipality of Svrljig (18.5) and the lowest in the municipality of Merošina (7.2). Conclusion: The registration of an unfavorable trend in the incidence of ovarian cancer indicates a lack of adequate primary and secondary prevention. It is necessary to effectively implement preventive measures and education of women in order to reduce risk factors and early detection of the disease.
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