Abstract
The prevalence and independent correlates of readmission for heart failure (HF) after transcatheter aortic valve replacement (TAVR) remain unclear in all-comers. We sought to evaluate the incidence, risk factors and clinical impact of readmission for HF after successful TAVR in an unselected patient population. All patients undergoing successful TAVR in two high-volume French centers from February 2010 to December 2016 were prospectively included. Cox multivariate model was used to assess risk factors of readmission for HF over one year follow up. A total of 1139 patients aged 82.4 ± 7.7 years were included. Half (52.2%) were male. Transfemoral access and balloon-expandable valve were most frequently used (82.4% and 60.7% respectively). Within one-year of follow-up, 99 (8.7%) patients were readmitted for heart failure. Mortality was increased by two-fold among patients readmitted for HF vs. those without readmission (22 [22.2%] vs. 123 [11.8%], HR 1.9; 95% CI [1.2–3.1], P = 0.004). Chronic pulmonary disease (adjHR 1.8; 95% CI [1.2–2.8], P = 0.008), chronic kidney disease (adjHR 1.7; 95% CI [1.1–2.6], P = 0.01), diabetes mellitus (adjHR 1.7; 95% CI [1.1–2.5], P = 0.01), prior atrial fibrillation (adjHR 1.6; 95% CI [1.1–2.4], P = 0.02) and post-TAVR left ventricular ejection fraction (LVEF) ≤35% (adjHR 2.1 95%CI 1.2–3.7, P = 0.009) independently predicted readmission for HF. Readmission for HF within one year of successful TAVR is frequent and associated with increased mortality. Comorbidities and post-TAVR LVEF ≤35% but not valvular-related factors are the main correlates of readmission for HF.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.