Abstract
BackgroundUterine leiomyomas are the most commonly observed pathologies, with an estimated prevalence of 4. 5–68.6%. We aimed to calculate myomectomy-related mortality and venous thromboembolism incidence rates in the Republic of Korea.MethodsThe data of patients who underwent myomectomy (2009–2018) were obtained from the Health Insurance Review and Assessment Service-National Inpatient Sample. The mortality rate after myomectomy was calculated using the leiomyoma diagnostic codes and myomectomy procedure codes. The incidence rates of venous thromboembolism, deep vein thrombosis, and pulmonary embolism were calculated using their diagnostic codes, with concomitant use of an antithrombotic agent during the same period or within 90 days after myomectomy.ResultsThe data of 23,549 women aged 15–55 years who underwent myomectomy were extracted. The myomectomy rate was 14.6 ± 0.1 per 10,000 patients. The average age was 39.39 ± 0.04 years. One patient who underwent myomectomy died; this patient did not have concomitant venous thromboembolism. The post-myomectomy mortality rate was 1.3 ± 0.8 per 10,000 patients. The incidence rates of venous thromboembolism, deep vein thrombosis, and pulmonary embolism after myomectomy were 5.7 ± 1.6 per 10,000 patients, 4.4 ± 1.4 per 10,000 patients, and 2.5 ± 1 per 10,000 patients, respectively. The conversion rate to hysterectomy was 2.9 ± 1.1 per 10,000 patients.ConclusionThe current mortality rate after myomectomy (0.013%) is substantially lower than that described in previous studies at the turn of the 20th century. The incidence of venous thromboembolism is also considerably lower than that in the general population worldwide.
Highlights
Commonly known as fibroids, are among the most common problems encountered by gynecologists, with a prevalence estimated at 4.5–68.6% [1]
The data of 23,549 women aged 15–55 years who underwent myomectomy were extracted from a database of 3,307,214 women, recorded between 2009 and 2018 (Figure 1)
The average age was 39.39 ± 0.04 years, and Venous thromboembolism (VTE) was reported in two patients
Summary
Commonly known as fibroids, are among the most common problems encountered by gynecologists, with a prevalence estimated at 4.5–68.6% [1]. A research by Baird et al showed that leiomyomas are discovered by ultrasonography in more than 80% of women of African lineage and in ∼70% of white women by the age of 50 years [2]. They frequently cause abnormal uterine bleeding and pelvic pain and are implicated in infertility. Many patients with symptomatic leiomyomas want to have the option of future childbearing or want to conserve their uterus. For these women, the removal of the leiomyomas alone with reconstruction and preservation of the uterus is a significant option. We aimed to calculate myomectomy-related mortality and venous thromboembolism incidence rates in the Republic of Korea
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