Abstract
Background. Surveillance represents a key strategy to control type 1 diabetes mellitus (T1DM). In Italy, national data are missing. This study aimed at evaluating the incidence of T1DM in subjects <18 year olds in Apulia (a large southeastern region, about 4,000,000 inhabitants) and assessing the sensitivity of the regional Registry of Childhood-Onset Diabetes (RCOD) in the 2009–2013 period. Methods. We performed a retrospective study matching records from regional Hospital Discharge Registry (HDR), User Fee Exempt Registry (UFER), and Drugs Prescription Registry (DPR) and calculated T1DM incidence; completeness of each data source was also estimated. In order to assess the RCOD sensitivity we compared cases from the registry to those extracted from HDR-UFER-DPR matching. Results. During 2009–2013, a total of 917 cases (about 184/year) in at least one of the three sources and an annual incidence of 25.2 per 100,000 were recorded, lower in infant, increasing with age and peaked in 5- to 9-year-olds. The completeness of DPR was 78.7%, higher than that of UFER (64.3%) and of HDR (59.6%). The RCOD's sensitivity was 39.05% (360/922; 95% CI: 34.01%–44.09%). Conclusions. Apulia appeared as a high-incidence region. A full, active involvement of physicians working in paediatric diabetes clinics would be desirable to improve the RCOD performance.
Highlights
Type 1 diabetes mellitus (T1DM), previously known as insulin-dependent, is a chronic disease that usually develops during childhood and adolescence
In order to estimate the incidence of type 1 diabetes mellitus (T1DM) we performed a retrospective study by using three data sources: (i) Hospital Discharge Registry (HDR), which collects data on discharge diagnoses and procedures of all patients admitted to hospitals: we extracted records of patients aged
Between 2009 and 2013, in Apulia, we identified a total of 4,642 hospitalizations for diabetes mellitus in subjects aged
Summary
Type 1 diabetes mellitus (T1DM), previously known as insulin-dependent, is a chronic disease that usually develops during childhood and adolescence. As one of the major chronic diseases during the age of development, with about 350 million people affected worldwide [1], the diabetes mellitus represents a public health problem in both low- and high-income countries [3]. In Norway, in the period 2004–2012 the average incidence rate of T1DM in children below 15 years of age was 32.7 per 100,000 personyears [10]. This study aimed at evaluating the incidence of T1DM in subjects
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have