Abstract

In the early work on the Rh factor, it was noticed that some bloods might be classified as Rh positive or Rh negative depending upon the human anti-Rh serum employed. It has been shown that human anti-Rh sera vary in their specificity, because they contain antibodies resulting from immunization to different Rh antigens. The anti-Rh sera that have thus far been found contain the following antibodies: anti-Rh0, anti-Rh′, anti-Rh″, anti-Rh′0 and anti-Rh″0. The anti-Rh0 sera correspond in specificity with anti-Rh sera obtained by immunizing animals with Macacus rhesus blood. The anti-Rh′0 contain two antibodies, anti-Rh0 and anti-Rhr′; this holds true for anti-Rh″0 containing antibody anti-Rh0 and anti-Rh″.1 Anti-Rh sera containing other antibody combinations have been found by British authors.2Employing the 3 different varieties of human anti-Rh sera containing only one antibody, 8 Rh types have been defined by Wiener,3 Rh0, Rh1, Rh2, Rh1Rh2, Rh′, Rh″, Rh'Rh″, and Rh negative. Type Rh1 may also be designated...

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