Abstract

The term secondary malignancy relates simply to the sequence of occurrence of malignancies in an individual patient, and it is not possible to derive a causality from this temporal sequence. Also, although there is no doubt that ionizing radiation and/or chemotherapy may induce malignancies, there are a number of other factors which may also cause malignant tumors. For the treating physician it is not only of interest to know the frequency of occurrence of secondary malignancies. He also has to follow any clues to the cause of secondary malignancies, because prophylactic steps can only be taken with knowledge of the causality.

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