Abstract
Objective: To determine the incidence of open neural tube defect (ONTD) in Asir Province, Southern region of KSA andcompare with eastern region and central region of the country and determine if the incidence is stable or changing over the years. Design:Prospective study. Period: January 2009 to December 2011 and retrospective study of the period March 2003 to January 2007. Materialand methods: We compared the number of newborns with ONTD for different periods. Results: Out of 18 patients in the prospectivegroup 12 were female and 6 male. The incidence is 1.34 per 1000 live births. Hospital Data from year 2003 to 2007 shows 32 totaladmissions for ONTD in 4 years. Conclusions: Comparison with eastern region and central regions gives a slightly high incidencecomparing 1.34/1000 live births to 1.09/1000 in central region and 0.97/1000 live births in eastern region. There is a decline in thenumber of ONTD cases in Asir Province, Southern region of Saudi Arabia.
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