Abstract
Incidence of nephrogenic systemic fibrosis after adoption of restrictive gadolinium-based contrast agent guidelines
Highlights
Incidence of Nephrogenic Systemic Fibrosis after Adoption of Restrictive Gadolinium-based Contrast Agent Guidelines Wang Y, Alkasab TK, Narin O, Nazarian RM, Kaewlai R, Kay J, Abujudeh HH Department of Radiology and Department of Pathology, Dermatopathology Unit, Massachusetts General Hospital, 55 Fruit St, FND 213B, Boston, MA 02114 Radiology. 2011; 260: 105-11
The guidelines (a) require a recent serum creatinine level measurement in any patient who is aged 60 years or older and/or at risk for renal disease, (b) limit the maximal weight-based gadolinium-based contrast agent (GBCA) dose administered to any patient with an estimated glomerular filtration rate lower than 60 mL/min/m(2)
The electronic medical records were searched for all contrast material-enhanced magnetic resonance (MR) imaging examinations performed during the post-guidelines adoption period between January 2008 and March 2010 and the pre-guidelines adoption and transitional period between January 2002 and December 2007
Summary
Incidence of Nephrogenic Systemic Fibrosis after Adoption of Restrictive Gadolinium-based Contrast Agent Guidelines Wang Y, Alkasab TK, Narin O, Nazarian RM, Kaewlai R, Kay J, Abujudeh HH Department of Radiology and Department of Pathology, Dermatopathology Unit, Massachusetts General Hospital, 55 Fruit St, FND 213B, Boston, MA 02114 Radiology. Purpose: To retrospectively determine the incidence of nephrogenic systemic fibrosis (NSF) in a large academic medical center after the adoption of restrictive gadolinium-based contrast agent (GBCA) administration guidelines.
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