Abstract

AbstractAt autopsy, 62 patients with rheumatoid arthritis (RA) showed significantly lower morbidity (P < 0.001) and mortality (P < 0.02) from myocardial infarction than 62 matched control patients, but there were no significant differences in frequency of cerebral infarction or pulmonary embolism. Coronary artery atherosclerosis occurred as frequently in the patients with RA as in the control population, suggesting that there may be a decreased tendency toward thrombosis in the rheumatoid group. Therapy with aspirin and the consequent inhibition of platelet aggregation may explain this observation.

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