Abstract

Objective: To determine the frequency of malignancy in multinodular goiter patients undergoing thyroid surgery in our institution. Place and duration of study: This is a prospective study was done on patients in the Department of general surgery, Liaquat University of Medical & Health Sciences Hospital Jamshoro, for the period of one year January 2011 to December 2011. Patients and Method: Total 95 cases with clinical diagnosis on multinodular were admitted through out patient department. All the data was recorded on predesigned Performa. Results : Total 95 patients with male to female ratio of 1:8.5Out of these 95 patients . Males patients were 10 (10.5%) and females 85 (89.5%) with the mean age of 36.24.on histopathological ground, 88 (92.63%) patients were benign Multinodular Goiter and 7 (7.37%) patients were diagnosed as having malignancy. Females were affected more commonly then male with F: M ratio 6:1. Among them, papillary carcinoma is more is the more common 5 (71.4%) patients, 1(14..3%) patient having follicular carcinoma and 1(14.3%) patient was diagnosed as a Medullary carcinoma. Conclusion: The risk of malignancy in Multinodular Goiter has not to be under estimated, and that a dominant nodule in Multinodular Goiter should be valued and majority of the patients with thyroid cancers presents multinodular goiter. Normal 0 false false false EN-US X-NONE AR-SA

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