Abstract
IntroductionVarious researches have stated the correlation between serum uric acid (sUA) and cardiovascular disease (CVD); however, no local studies are available. In this study, we will determine the prevalence of hyperuricemia in patients with acute myocardial infarction and compare with the control group.MethodsThis case-control study was conducted from March to November 2019 in the tertiary care hospital in Pakistan. In all, 119 patients with acute myocardial infarction were enrolled in this study, and 119 controls were identified from the outpatient department. Their sUA levels were measured within 24 hours of acute myocardial infarction.ResultsThe mean sUA levels were significantly higher in patients with acute myocardial infarction (AMI) in comparison to the control group (6.17 ± 2.12 vs. 5.51 ± 1.89, p-value; 0.01). Overall, there were more patients with hyperuricemia in the case group compared to the control group (47.89% vs. 33.6%, p-value = 0.04)ConclusionIn this study, after adjustment of other known factors, hyperuricemia is associated with AMI. Efforts should be made to include screening for hyperuricemia in patients with a high risk of myocardial infarction.
Highlights
Various researches have stated the correlation between serum uric acid and cardiovascular disease (CVD); no local studies are available
The mean serum uric acid (sUA) levels were significantly higher in patients with acute myocardial infarction (AMI) in comparison to the control group (6.17 ± 2.12 vs. 5.51 ± 1.89, p-value; 0.01)
Hyperuricemia has been correlated with various diseases such as hypertension, hyperlipidemia, diabetes, metabolic syndrome, and renal disease, which all have contributed to increased coronary heart disease (CHD) and all-cause mortality
Summary
Various researches have stated the correlation between serum uric acid (sUA) and cardiovascular disease (CVD); no local studies are available. We will determine the prevalence of hyperuricemia in patients with acute myocardial infarction and compare with the control group
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