Abstract

Background: In Macedonia of 2008 year to enroll 9500 diseased sheeps and goats of Brucellosis.That is too much potential to appear of human Brucellosis.The same year to records 213 new diseased peoples of human Brucellosis who is significant health problem many years ago. Methods: It used descriptive-epidemiological method,biochemical and serological analysis (BAB,Wight,Coombs) to follow up a ten years period to diseasse (1998-2008) in General hospital-Gevgelia,Macedonia. Results: In the department of Infectious disseases-Gevgelia for period of ten years are treated totally 135 diseased persons.The last year to appear one outbreak of human Brucellosis to one lifestock farm with 15 diseased peoples.In the season(march-september) to enroll 108(80.0%)patients.The structure of diseased peoples moreover was sheep-breeders and theirs own family,farmers,housewifes and veterinary surgeons.Most frequently age group was 35-45 years of 62 (45.0%) patients).The smallest number of patients to enroll 2005 year (6).The last year have to biggest number of patients (20).Clinical manifestation of illness was pains at knees,hips,shoulders e.t.c.Not often clinical manifestations was high temperature, night perspiration,weakness,exhausting.More frequently complications was hepatitis brucellogenes (22,2%),orhyepidydymitis (5,9%),endocarditis (1,5%) and bronchopneumonia (0,7%).Therapeutical treatmen was introduced during of six weeks with dual therapy with(Rifampicin,Doxiciklin/Co-trimoxsol). Conclusion: The very much numbers of diseased animals (sheeps and goats) to 9500 of last year subsequently to introduce very high infectious potential to appear of human Brucellosis at Republic of Macedonia.Risk group to obtaining human Brucellosis was farmeres and theirs own family, house- wifes whos to handles whit animal products,veterinary surgeons e.t.c. Most frequently complication was hepatits brucellogenes (22.2%) with auspicious course. To preventing to this zoonosis should complete vaccination and eradication to diseased stock. Abstracts for SupplementInternational Journal of Infectious DiseasesVol. 14Preview Full-Text PDF Open Archive

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