Abstract
Background: To find the incidence of Granulomatous mastitis at Saveetha Medical College and Hospital for a period of past two years.
 Methods: Retrospective study Incidence of Granulomatous Mastitis at Saveetha Medical College and Hospital for the past two years. The specimens were received from the histopathology section of the pathology department. Detailed gross examination of the specimen was done. This was followed by fixation and staining, done using hematoxylin and eosin stains.
 Results: In the period of two years from 2019 to 2020, 10 cases have been reported . Out of which five cases belonged to the reproductive age group, two cases in the post menopausal age group and three cases belonged to peri menopausal age group.
 All the patients presented with a lump on the breast and abscess. The treatment consists of corticosteroid therapy and minimal surgical intervention.
 Conclusion: Granulomatous mastitis is an inflammatory condition that mimics carcinoma of breast. Hence diagnosis is mainly made through exclusion and examination of histopathology slides. Core needle biopsy is the gold standard technique used in the diagnosis of the condition. It’s a self limiting disease, and requires surveillance,corticosteroid therapy and surgical intervention.
Highlights
IntroductionGranulomatous mastitis is a rare chronic inflammatory condition of the breast, with no known etiology [1]
Granulomatous mastitis is a rare chronic inflammatory condition of the breast, with no known etiology [1]. It can occur as a secondary complication of tuberculosis, sarcoidosis.It can be divided into two categories, one being idiopathic, and the other occurring as a secondary complication [2]
Corticosteroid therapy is recommended for a period of 6 months
Summary
Granulomatous mastitis is a rare chronic inflammatory condition of the breast, with no known etiology [1]. It can occur as a secondary complication of tuberculosis, sarcoidosis.It can be divided into two categories, one being idiopathic (granular lobar mastitis), and the other occurring as a secondary complication [2]. Granulomatous mastitis is composed of chronic inflammatory infiltrates and shows clusters of histiocytes and multi nucleated giant cells (granulomata). These lesions rarely show necrosis unlike tuberculosis of the breast [4]. Conclusion: Granulomatous mastitis is an inflammatory condition that mimics carcinoma of breast. It’s a self limiting disease, and requires surveillance,corticosteroid therapy and surgical intervention
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