Abstract
Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population. In total 5072 people older than 18 years,were randomly selected from all over Spain). Socio-demographic and clinical data, survey on habits (physical activity and food consumption) and weight, height, waist, hip and blood pressure were recorder. A fasting blood draw and an oral glucose tolerance test were performed. Determinations of serum glucose were made. In the follow-up the same variables were collected and HbA1c was determined. A total of 2408 subjects participated in the follow-up. In total, 154 people developed diabetes (6.4% cumulative incidence in 7.5 years of follow-up). The incidence of diabetes adjusted for the structure of age and sex of the Spanish population was 11.6 cases/1000 person-years (IC95% = 11.1–12.1). The incidence of known diabetes was 3.7 cases/1000 person-years (IC95% = 2.8–4.6). The main risk factors for developing diabetes were the presence of prediabetes in cross-sectional study, age, male sex, obesity, central obesity, increase in weight, and family history of diabetes. This work provides data about population-based incidence rates of diabetes and associated risk factors in a nation-wide cohort of Spanish population.
Highlights
Type 2 diabetes is a potentially preventable disease[7,8], and the studies on its incidence have led to examination of the variables associated with a greater risk for developing this disease
Type 2 diabetes is a polygenic disease very influenced by environmental factors and, it is necessary to perform specific population-based incidence studies, as recommended by the International Diabetes Federation (IDF)[9]
The objective of the present study was to describe the incidence of diabetes in Spain through the re-evaluation of this cohort, as well as to examine the main risk factors related to development of diabetes
Summary
Type 2 diabetes is a potentially preventable disease[7,8], and the studies on its incidence have led to examination of the variables associated with a greater risk for developing this disease. Type 2 diabetes is a polygenic disease very influenced by environmental factors and, it is necessary to perform specific population-based incidence studies, as recommended by the International Diabetes Federation (IDF)[9]. Of special interest are the studies at national level, which include results about the differences among natural populations and are necessary for national health systems to implement screening and prevention programs as basic tools to prevent the epidemic
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