Incidence of catheter-related venous thromboembolism in peripherally inserted central venous catheters vs tunneled chest central venous catheters in patients with hematologic malignancies.

Abstract

e20684 Background: Common complications of central venous catheters (CVCs) include catheter-related venous thromboembolism (CR-VTE) and central line-associated blood stream infections (CLABSI). In an effort to decrease CR- VTE rates, in 5/2012 the Medical College of Wisconsin (MCW) HM group changed the placement of CVCs from brachiocephalic vein PICCs to tunneled chest internal jugular vein CVCs in all patients with HMs unless contraindicated. Methods: We report CR-VTE and CLABSI rates pre- and post-intervention between 1/2009-6/2013. Clinical data were collected through the electronic medical record. All comparisons were using Fisher’s exact Chi-square test. Results: From 1/2009-6/2013, 1,953 CVCs were placed in patients at MCW with HMs. The table shows the significant decrease in overall incidence of VTEs (p < 0.01) with stable incidence of CLABSIs (p = 0.15) following a change to placement of tunneled CVCs. There was no statistical difference between disease types. Conclusions: The HM group at MCW inst...