Abstract
Introduction: Despite different ICU admission causes, ventilator-associated event (VAE) is still a common cause of mortality and morbidity in intubated patients and impedes obvious progression in diagnostic modalities and management of these infections. Objectives: The aim of this study was to estimate VAE incidence, detection of antimicrobial resistance pattern’s which can help in the management and to follow the outcome of the patients having VAE. Materials and methods: This was a retrospective study done over a period of 24months from January 2018 to December 2019 in a tertiary care hospital in Bangalore. The study population included all the confirmed VAE patients. Their incidence of microbiological profile and the outcome was noted. Results: Out of 422 mechanical ventilated (MV) patients 71 patients developed VAE. In the 71 proved VAE cases 48 (67.6%) were male and23 (32.4%) were females. Out of 71 cases, the mean age who were having VAE falls in the range of 65- 75 yrs. The incidence of VAE is 16.82 and the incidence density:9.78 /1000 ventilator days. Klebsiella pneumonia (29.5%) was the common organism isolated among 71 cases. Conclusion: Utilizing the preventive, diagnostic, and treatment recommendations outlined should allow for improved outcomes for a common and serious medical complication seen in ICU mechanically ventilated patients.
Highlights
Despite different ICU admission causes, ventilator-associated event (VAE) is still a common cause of mortality and morbidity in intubated patients and impedes obvious progression in diagnostic modalities and management of these infections
The present study retrospectively reviewed all the adult cases who were intubated and under mechanical ventilation in ICU and diagnosed the VAE in them by standard criteria according to the recent guidelines by Centre for Disease Control (CDC)
Knowledge of local antibiograms should guide the choice of antibiotics, in addition to the likelihood of organisms
Summary
Despite different ICU admission causes, ventilator-associated event (VAE) is still a common cause of mortality and morbidity in intubated patients and impedes obvious progression in diagnostic modalities and management of these infections. The study population included all the confirmed VAE patients Their incidence of microbiological profile and the outcome was noted. Ventilator-associated event pneumonia is pneumonia that develops 2–3 days after endotracheal intubation; the patient must have new or progressive radiological infiltrate, infection alerts (e.g. fever, white blood cell count change), altered sputum characters, and isolation of a causative organism, all together to diagnose VAE [5]. VAE is still one of the most common hospitalacquired infections that are encountered in ICU patients despite the recent progress in diagnostic modalities and management advances of these infections [6]
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