Abstract
BackgroundTo estimate the incidence and risk factors for mortality in HIV-1-infected patients in China.MethodsInformation on AIDS-related deaths was collected from the Chinese Center for Disease Control and Prevention’s Disease Surveillance Information Reporting System and AIDS Prevention and Control Information System.ResultsA total of 379,348 HIV cases were recorded in the databases from 2006. Among those, 138,288 patients were reported as having developed AIDS and 72,616 (19%) died of AIDS after data was extracted from the databases in January 2011. Mortality was higher among those patients aged 50 years old or older (AOR: 3.41, CI: 1.47-7.91) who had been infected by intravenous drug use (AOR: 1.65, CI: 1.28-2.14) or blood transfusion/donation (AOR: 2.18: 1.18-3.99). Compared to patients who had not initiated highly active antiretroviral therapy (HAART), those who had initiated HAART were more likely to have a long interval of time between infection confirmation and AIDS-related death.ConclusionsThe effective reduction of AIDS mortality could be improved through timely treatment.
Highlights
To estimate the incidence and risk factors for mortality in HIV-1-infected patients in China
The effective reduction of AIDS mortality could be improved through timely treatment
This study presents data from the China Disease Prevention and Control Information System on changes in AIDS mortality through December 31, 2010
Summary
To estimate the incidence and risk factors for mortality in HIV-1-infected patients in China. HIV in China; at the end of 2011, the cumulative number of reported deaths since the beginning of the HIV epidemic was 93,000 [1]. A report released by the Ministry of Health in 2009 showed that HIV/AIDS had become the leading cause of death from infectious disease in China [2]. HAART has contributed additional benefits such as prolonged disease-free survival, durable HIV virologic suppression, immunologic (CD4 cell) repletion, and Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China reductions in hospitalization rates [14,18,19]. As a result of the Chinese government scaling up the National Free
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
