Abstract

BackgroundHemorrhage is the main cause of maternal death during pregnancy. This study aims to evaluate incidence and outcomes of Severe Ante Partum Hemorrhage (SAPH) during the third trimester of pregnancy prior to delivery.MethodsAnalytical cross-sectional study with prospective data collection during 12 months in Yalgado Ouedraogo Hospital, Ouagadougou, Burkina Faso. In this context SAPH is specifically referring to Ante Partum Hemorrhage (APH) and Intra Partum Hemorrhage (IPH) in the 3rd trimester. Postpartum Hemorrhage (PPH) was not included.ResultsDuring our study 7,469 women were admitted in obstetrics and 122 cases of SAPH were recorded. SAPH represented 1.6% (n = 122) of hospitalizations causes and 14.5% (n = 1083) of hemorrhages during pregnancy. Mean age was 27.8 ± 6.9 years, mean parity 2.8 ± 1.3 and mean duration of pregnancy was 37 Weeks Amenorrhea (WA). Evacuation from other facilities was the main mode of admission (91.8%, n = 112) and blood transfusion was the essence of resuscitation. Complications were observed in 80.3% (n = 98). During the study, 118 maternal deaths were reported of which 15.6% (n = 19) related to SAPH. Among SAPH cases who died (n = 19) majority (n = 16) had severe anemia (n = 16; 82.6%, p = 0.004). Ten women (8.19%) were admitted in Intensive Care Unit (ICU). Fifteen premature births (12.3%) and 22 perinatal deaths (18.1%) were recorded. Evacuation (p = 0.04), critical clinical condition during admission (p = 0.004), and Uterine Rupture (UR) (p = 0.002) were associated with poor outcome. The Retroplacental Hemorrhage (RPH) (40.9%) was the most common cause of fetal death (p = 0.005) and was associated with High Blood Pressure (HBP) and pre-eclampsia.ConclusionAPH is a complication associated with significant maternal and fetal morbidity and mortality.

Highlights

  • Hemorrhage is the main cause of maternal death during pregnancy

  • Serious obstetrical hemorrhage is referring to Antepartum Hemorrhage (APH) and intrapartum hemorrhage (IPH) in the 3rd trimester

  • According to a World Health Organization (WHO) study in Sub-Saharan Africa, APH accounts for 8.4% of all maternal hemorrhage versus 0.9% for IPH3

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Summary

Introduction

Hemorrhage is the main cause of maternal death during pregnancy. [1] Direct obstetrical complications are the main causes of maternal deaths, with bleeding [2] identified as the first cause. In Burkina Faso maternal mortality remains high, with 2,700 deaths per 100,000 deliveries [1]. Hemorrhage is the leading cause of maternal mortality globally, accounting for approximately 27% of deaths worldwide; this includes postpartum, intrapartum and antepartum hemorrhage [3]. Hemorrhage prior to delivery accounts for only 16.3% of maternal deaths, while Sub-Saharan Africa remains high at 24.5%. Worldwide postpartum hemorrhage (PPH) has been well studied, but APH and intrapartum hemorrhage (IPH) are less well-documented. During APH, complications can be fetal as well as maternal. Various fetal complications are prematurity, low birth weight, intrauterine death, congenital malformation and birth asphyxia [7]

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