Abstract
BackgroundThe lack of epidemiologic information on osteoporotic hip fractures hampers the development of preventive or curative measures against osteoporosis in South Korea. We conducted a population-based study to estimate the annual incidence of hip fractures. Also, we examined factors associated with post-fracture mortality among Korean elderly to evaluate the impact of osteoporosis on our society and to identify high-risk populations.MethodsThe Korean National Health Insurance (NHI) claims database was used to identify the incidence of hip fractures, defined as patients having a claim record with a diagnosis of hip fracture and a hip fracture-related operation during 2003. The 6-month period prior to 2003 was set as a 'window period,' such that patients were defined as incident cases only if their first record of fracture was observed after the window period. Cox's proportional hazards model was used to investigate the relationship between survival time and baseline patient and provider characteristics available from the NHI data.ResultsThe age-standardized annual incidence rate of hip fractures requiring operation over 50 years of age was 146.38 per 100,000 women and 61.72 per 100,000 men, yielding a female to male ratio of 2.37. The 1-year mortality was 16.55%, which is 2.85 times higher than the mortality rate for the general population (5.8%) in this age group. The risk of post-fracture mortality at one year is significantly higher for males and for persons having lower socioeconomic status, living in places other than the capital city, not taking anti-osteoporosis pharmacologic therapy following fracture, or receiving fracture-associated operations from more advanced hospitals such as general or tertiary hospitals.ConclusionThis national epidemiological study will help raise awareness of osteoporotic hip fractures among the elderly population and hopefully motivate public health policy makers to develop effective national prevention strategies against osteoporosis to prevent hip fractures.
Highlights
IntroductionKnowledge regarding the incidence of hip fractures and their outcomes, including mortality, is needed to evaluate the impact of osteoporosis on our society, to identify high-risk populations, and to help health care decision-makers allocate scarce resources and prioritize hip fractures along with other important clinical problems
The lack of epidemiologic information on osteoporotic hip fractures hampers the development of preventive or curative measures against osteoporosis in South Korea
The study results are expected to increase our understanding of the magnitude of the elderly population suffering from hip fractures and to urge public health policy makers to develop effective national prevention strategies for osteoporosis
Summary
Knowledge regarding the incidence of hip fractures and their outcomes, including mortality, is needed to evaluate the impact of osteoporosis on our society, to identify high-risk populations, and to help health care decision-makers allocate scarce resources and prioritize hip fractures along with other important clinical problems. South Korea operates a mandatory universal health insurance system, with a centralized healthcare claims database that provides a unique nationwide source of information on health care resource utilization We used this database to estimate the annual incidence and 1-year mortality of hip fractures in Koreans over the age of 50. The study results are expected to increase our understanding of the magnitude of the elderly population suffering from hip fractures and to urge public health policy makers to develop effective national prevention strategies for osteoporosis
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