Incidence and mortality of female breast cancer in Jiangsu, China.

Li-Zhu Wu,Jin-Yi Zhou,Ming Wu,Yun Qian,Ren-Qiang Han,Mei-Hua Dong,Jie Yang

doi:10.7314/apjcp.2014.15.6.2727

Li-Zhu Wu, Jin-Yi Zhou + Show 5 more

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https://doi.org/10.7314/apjcp.2014.15.6.2727

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Abstract

The aim of this study was to describe and analyze the incidence and mortality of female breast cancer in Jiangsu Province of China. Incidence and mortality data for female breast cancer and corresponding population statistics from eligible cancer registries in Jiangsu from 2006 to 2010 were collected and analyzed. Crude rates, age-specific rates and age-standardized rates of incidence and mortality were calculated, and annual present changes (APCs) were estimated to describe the time trends. From 2006 to 2010, 11,013 new cases and 3,068 deaths of female breast cancer were identified in selected cancer registry areas of Jiangsu. The annual average crude incidence and age-standardized incidence by world population (ASW) were 25.2/ and 17.9/100,000 respectively. The annual average crude and ASW for mortality rates were 7.03/ and 4.81/100,000. The incidence was higher in urban areas than that in rural areas, and this was consistent in all age groups. No significant difference was observed in mortality between urban and rural areas. Two peaks were observed when looking at age-specific rates, one at 50-59 years and another at over 85 years. During the 5 years, incidence and mortality increased with APCs of 4.47% and 6.89%, respectively. Compared to the national level, Jiangsu is an area with relatively low risk of female breast cancer. Breast cancer has become a main public health problem among Chinese females. More prevention and control activities should be conducted to reduce the burden of this disease, even in relatively low risk areas like Jiangsu.

Highlights

Breast cancer is the most common malignancy among women in the world (Jemal et al, 2011)
The incidence was higher in urban areas than that in rural areas, and this was consistent in all age groups
The risk of breast cancer is relatively lower in China than in developed countries, the incidence and mortality of this disease have been sustainably increased in the past decades (Yang et al, 2006)

Summary

Introduction

Breast cancer is the most common malignancy among women in the world (Jemal et al, 2011). The risk of breast cancer is relatively lower in China than in developed countries, the incidence and mortality of this disease have been sustainably increased in the past decades (Yang et al, 2006). According to the latest Chinese Cancer Registry Annual Report (Hao and Chen, 2012), breast cancer has become the most common cancer occurred among Chinese women and ranked the fifth leading cause of female cancer deaths in 2009. The age-standardized rate of incidence and mortality by world standard population (ASW) was 29.0 and 6.56 per 100,000 in Chinese females, respectively. As the national cancer registry system has not been well established yet, the distribution of cancer including breast cancer in China still need to be further depicted. Jiangsu Province is one of the developed coastal areas in

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