Abstract
The 1,2-migration of an ethylthio group with inversion of configuration at the C-1 and C-2 atoms was observed during the attempted preparation of 2,3-orthoester derivatives of ethyl 1-thio-α- l-rhamnopyranoside. The rearrangement leading to the formation of methyl 2-thio-β- l-glucopyranosides could be avoided by preparing the orthoester in DMF rather than in acetonitrile and by using a controlled amount of acid catalyst.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
