Abstract
A versatile, operationally simple and highly efficient one-pot three-component approach for the synthesis of spiro oxazolidine oxindole derivatives has been developed by the domino reaction of isatins, arylacetylenes, and N-tosyl aldimines in acetonitrile catalyzed by InBr3 at ambient temperature. The significant advantages of this protocol are highlighted by excellent yields, cleaner reaction profiles, avoidance of toxic catalyst, broader substrate scope, and successful assembly of three new C–C, C–N and C–O bonds.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
