Abstract

Life threatening opioid toxicity is a rare but recognised complication of opioid use. In 2014, NHS England released a patient safety alert on inappropriate prescribing of naloxone in patients with chronic opioid use, citing two fatal cases.1 A retrospective audit (2017) of naloxone use in an acute hospital demonstrated that 90% (18/20) of administrations did not meet recommended standards. This prompted a quality improvement project to improve practice. A trust guideline was developed using the Palliative care formulary and UK Medicines Information's naloxone evidence review.2,3 This was disseminated through education sessions and email updates. An alert …

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