Abstract

Inappropriate empirical antibiotic therapy was an independent risk factor of pediatric persistent S. aureus bloodstream infection. Pediatric persistent S. aureus bloodstream infection was associated with metastatic infection and septic shock. • Pathogenic features such as Methicillin-resistant S. aureusand sources of infection such as central venous catheterrelated infection were risk factors of PSBSI in adults. • PSBSI increased the incidence of metastatic infection and mortality in adults. • Inappropriate empirical antibiotic therapy was an independent risk factor of pediatric persistent S. aureus bloodstream infection. • Pediatric persistent S. aureus bloodstream infection was associated with metastatic infection and septic shock.

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