Abstract
Background: In the care of women with gestational diabetes mellitus (GDM), more attention is put on glycemic control than in factors such as gestational weight gain (GWG). We aimed to evaluate the rate of inadequate GWG in women with GDM, its clinical predictors and the association with pregnancy outcomes. Methods: Cohort retrospective analysis. Outcome variables: GWG according to Institute of Medicine 2009 and 18 pregnancy outcomes. Clinical characteristics were considered both as GWG predictors and as covariates in outcome prediction. Statistics: descriptive, multinomial and logistic regression. Results: We assessed 2842 women diagnosed with GDM in the 1985–2011 period. GWG was insufficient (iGWG) in 50.3%, adequate in 31.6% and excessive (eGWG) in 18.1%; length of follow-up for GDM was positively associated with iGWG. Overall pregnancy outcomes were satisfactory. GWG was associated with pregnancy-induced hypertension, preeclampsia, cesarean delivery and birthweight-related outcomes. Essentially, the direction of the association was towards a higher risk with eGWG and lower risk with iGWG (i.e., with Cesarean delivery and excessive growth). Conclusions: In this cohort of women with GDM, inadequate GWG was very common at the expense of iGWG. The associations with pregnancy outcomes were mainly towards a higher risk with eGWG and lower risk with iGWG.
Highlights
Gestational diabetes mellitus (GDM) entails risks for the mother and the newborn, both at short and long-term [1,2]
The risk of large for gestational age (LGA) was double with excessive GWG (eGWG) and 0.70 with insufficient GWG (iGWG) [13]. Articles addressing this point in our background are limited [17,18,19] and, we aimed to evaluate the frequency of inadequate gestational weight gain (GWG) in women with gestational diabetes mellitus (GDM) attended in our center, its clinical predictors and the association with pregnancy outcomes
A total of 2842 pregnant women with GDM were attended during the period and information regarding GWG according to Institute of Medicine (IOM) and potential predictors was available in 2700 (2594 with singleton pregnancies, 106 with multiple pregnancies, 95.0% of the target population), with analyses being performed in this group
Summary
Gestational diabetes mellitus (GDM) entails risks for the mother and the newborn, both at short and long-term [1,2]. Gestational weight gain (GWG) is related to adverse pregnancy outcomes. In the general obstetric population, excessive GWG (eGWG) is associated with a higher risk of hypertensive disorders of pregnancy, GDM, caesarean section, postpartum weight retention, large for gestational age (LGA) and macrosomic newborns [9,10]. Insufficient GWG (iGWG) is associated with a higher risk of preterm birth and small for gestational babies (SGA) [11,12,13]. We aimed to evaluate the rate of inadequate GWG in women with GDM, its clinical predictors and the association with pregnancy outcomes. GWG was associated with pregnancy-induced hypertension, preeclampsia, cesarean delivery and birthweight-related outcomes. Conclusions: In this cohort of women with GDM, inadequate GWG was very common at the expense of iGWG. The associations with pregnancy outcomes were mainly towards a higher risk with eGWG and lower risk with iGWG
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
