Abstract

Aims: to evaluate the inadequacy of food consumption and the estimated nutrient depletion caused by the use of drugs in the elderly.Methods: a cross-sectional population study, attended by 427 elderly. Food consumption was obtained from the 24-hour Food Recall Survey and the Research Dietetic History. The use of drugs was assessed by a pharmacotherapeutic questionnaire.Results: 85.8% of elderly use medications, the most prevalent inhibitors angiotensin converting enzyme inhibitor (29.2%), acetylsalicylic acid (28.7%), hydrochlorothiazide (24.4%), hydroxymethyl-glutaryl coenzyme A reductase enzyme inhibitor (17.0%), calcium carbonate (12.6%) and proton pump inhibitors (8.2%). Acetylsalicylic acid, hydrochlorothiazide and proton pump inhibitors are the drugs that possibly deplete the greatest number of nutrients. Users of hydroxymethyl-glutaryl coenzyme A reductase enzyme inhibitor, 97% could had inadequate for vitamin E; of potassium-sparing diuretics, 90.0% of inadequacy for magnesium; digoxin, 83.3% of inadequate for magnesium and 58.3% for calcium and potassium.Conclusions: the drugs most commonly used by elderly are responsible for the depletion of numerous micronutrients, often associated with a high prevalence of inadequate consumption, which may cause possible nutritional deficiencies.

Highlights

  • Mesmo em casos de sobrepeso e de obesidade, a perda de peso em idosos eleva consideravelmente o risco de quedas, fraturas, institucionalização, fragilidade e morte[4]

  • the estimated nutrient depletion caused by the use of drugs

  • by 427 elderly. Food consumption was obtained from the 24-hour Food Recall Survey

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Summary

Introduction

Mesmo em casos de sobrepeso e de obesidade, a perda de peso em idosos eleva consideravelmente o risco de quedas, fraturas, institucionalização, fragilidade e morte[4]. Foram selecionados os fármacos ou classes farmacológicas mais utilizadas e responsáveis pela perda de nutrientes[11,12], tais como: ácido acetilsalicílico, digoxina, verapamil, furosemida, hidroclorotiazida, metformina, carbonato de cálcio, diurético poupador de potássio, anti-hipertensivo inibidor da enzima conversora de angiotensina, antiulceroso antagonista dos receptores de histamina H2, antiulceroso inibidor da bomba de prótons, hipolipemiante inibidor da enzima hidroximetil-glutaril coenzima A redutase, antidepressivo inibidor seletivo da recaptação de serotonina.

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