Abstract
Naegleria fowleri is a free‐living protozoan that causes the fatal disease primary amoebic meningoencephalitis. The only cases associated with drinking water have occurred in Australia and Arizona. One study found N. fowleri in 8% (n = 143) of all municipal untreated drinking water wells tested. The C × T values (concentration × contact time) for chlorine inactivation of N. fowleri trophozoites and cysts at an average disinfectant concentration of 1 mg/L were determined using the efficiency factor Hom kinetic model. The estimated C × T values for N. fowleri cysts are comparable to the published values for Giardia lamblia cysts, but are lower than those for Cryptosporidium parvum oocysts. In this study, the ultraviolet light dosage required to inactivate the cyst stage of N. fowleri was determined to be greater than that of Cryptosporidium oocysts but less than that of Acanthamoeba cysts.
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