Abstract

Dry preparations of T-1 bacteriophage were irradiated with helium ions and with stripped carbon and oxygen ions, extending previous studies of effect of LET to values unattainable with alpha -particles. Over a wide range in LET the effect on phage survival is a function only of the radiation dose, but for heavy ions the efficiency does decrease. A minimum requirement of either one or two ions in a track interval only a few angstrom units long is indicated for inactivation of plaque survival. The indication is against a higher minimum number of ions required. On interpretation in terms of target area, correction for -rays brings the phage target within morphological bounds.

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